The book publishing industry has always been linked inexorably to the dissemination of knowledge. Publishing and associated printing activities relied on long-standing and proven old technologies to provide a definitive linear progression for the creation of content in print form, providing clear implications for business processes and relationships with the various stakeholders. However, the emergence and development of digital technology may have significant effects on the book publishing industry. Thus the study sought to analyze the effect of digital technologies on business strategies adopted by publishers in Kenya. The study used a cross-sectional study design and employed census approach in the collection of data from all the 86 registered book publishers in Kenya. The sample size of the study was 258, with three respondents per publisher. Purposive sampling was used to select key respondents to participate in the study. Data was collected from participants through an online survey questionnaire that was both closed and open-ended. The data collected was then analyzed through the statistical package for social sciences (SPSS) with results presented through tables, frequencies, and charts. ANOVA was performed in the study. The study results established that all the publishers have made an investment in digital technologies in one way or the other, with the study establishing a bias towards print technology, internet technologies, and E-books/CDs. The study results indicated that there is a significant relationship between internet technologies and business strategies of book publishers. This was indicated with a p-value of 0.036. E-business technologies were found to have no significant relationship with business strategies as shown with a p-value of 0.53. Additionally, the study confirmed that print technologies affect the business strategy of firms as shown with a P-value of 0.04. Overall, the study found out that digital technologies have a low significant effect on business strategy as indicated with an R2 value of 9.7%. From the study results, it can be concluded that digital technologies affect the business strategies of book publishers and thus the need for book publishers to adopt digital business strategies.A dissertation submitted in partial fulfillment of the requirements for the award of master’s degree in corporate management in the school of business and public management at KCA university October 2016